Training four times a week throughout and the scale has barely acknowledged it, which is demoralising in a way I did not expect.
The question I want answered is what training is actually for during a large deficit, because framing it as calorie burn sets people up to quit when the arithmetic disappoints them.
I would rather have one careful answer than five confident ones.
Taking the question as asked, rather than the general version of it. The mechanism that matters here is not stomach emptying, it is central. GLP-1 receptor agonism in the arcuate nucleus stimulates POMC neurons and suppresses AgRP/NPY signalling, which is why the effect is appetite and food salience rather than physical fullness. Delayed gastric emptying largely tachyphylaxes over the first months; the appetite effect does not.
labquiet_amy said:The mechanism that matters here is not stomach emptying, it is central.
All true, with one condition: that curve is for people who reached the dose on schedule. Anyone who slowed the ladder for tolerability is on a different, flatter curve, and comparing yourself with the published mean will make you feel like a non-responder when you are not.
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Shop Reference StandardsRunnerRach said:Training four times a week throughout and the scale has barely acknowledged it, which is demoralising in a way I did not expect.
Agreed, though "tolerable" needs defining. A dose you tolerate by eating almost nothing is not tolerated, it is being paid for somewhere else — usually in lean mass, sometimes in adherence three months later.
From the other side of the consultation, briefly.
Pet owner bonus of training: my dog is also losing weight because we're walking 2-3x more than before. His vet is thrilled. 🐕
We went from a 15-minute shuffle around the block to 60-minute walks through the neighborhood. He's more energetic, I'm more energetic, and we're both healthier.
Get a dog. Or borrow one. Walking a dog is the best low-impact exercise motivation that exists. They never let you skip a walk. 🐾