amsterdam_pete ↑ said:

Plateau breaking story with a stall: I stalled at 205 lbs for 6 weeks.

amsterdam_pete has the substance of this right. The condition it depends on is worth stating. Most reported plateaus are not plateaus. Weight is a noisy signal — daily variation of one to two kilograms from glycogen, sodium and gut contents — so a fortnight of flat readings is well inside the noise band. Before concluding anything, look at a rolling weekly average over at least four weeks and at a tape measure, because recomposition shows up in circumference before it shows up in weight. Then track intake honestly for a week: appetite suppression fades unevenly, and intake creeping back up is the single commonest cause.

mel_PDX ↑ said:

Thirteen weeks at the same dose with no change on the scale, and I have gone from assuming it was the drug to assuming it was me and back several…

Can confirm. Same sequence, different timescale.

Adding the clinical framing, because it changes how the question reads. The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either. Those three things can all be true at once, and most arguments here are two people holding different parts of that.