Clinical perspective, offered as context rather than as advice. Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then measure again under the same conditions.
Happy to go further on any of that.
PedsEndoPhilly said:Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then…
Same experience, arrived at from the opposite direction. The detail I would add is minor and it is already implied above.
PedsEndoPhilly said:Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then…
There is a second half to this that has not been said yet. A defensible baseline is short: HbA1c and fasting glucose, a lipid panel with ApoB if you can get it, ALT and AST, creatinine with eGFR, TSH, ferritin and B12, and a full blood count. That set catches the things that change, the things that explain symptoms, and the things that alter the prescribing decision. Almost everything else on the long circulating lists is either invariant, uninterpretable without a specific question, or an incidental finding waiting to cause an unnecessary workup.
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Shop Reference StandardsOne concrete data point for the thread. For anyone reading later: the numbers in this thread are worth checking against a primary source before you act on them, including mine. Half the figures circulating in this community trace back to a secondary summary that dropped a qualifier.
A narrower follow-up, since the general answer is now clear:
How often to repeat it, because quarterly seems to be the convention and I cannot find the reasoning?