Dr.LipidDallas said:Semaglutide structural biology relevant to the pharmacology: semaglutide is a 31-amino acid peptide with 94% homology to native GLP-1(7-36).
No disagreement, though it depends on where somebody is starting from, and this thread has been assuming a starting point nobody stated.
That is the short version; the long version is somebody else's post.
DeniseRN_TPA said:The mechanism is more central than most summaries suggest.
This answered a question I did not know how to ask. Adding it to my notes with a link back to this thread.
Dr.LipidDallas said:Semaglutide structural biology relevant to the pharmacology: semaglutide is a 31-amino acid peptide with 94% homology to native GLP-1(7-36).
Filing a mild objection. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. Pushing back on the anecdote-stacking. Twenty people reporting the same thing is twenty samples from the same self-selected pool, not twenty independent confirmations.
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Shop Reference StandardsAdding the numbers, since they settle part of this. If you are going to change something, change one thing and give it long enough to express itself. Four weeks is the usual minimum for anything pharmacological on this board, and two weeks of data has told you almost nothing.