Dr.ObesityLA said:The mechanism and the magnitude are separate questions.
I would rather people stopped quoting the 24% as if it were a licensed outcome. It is a phase 2 result in a few hundred participants with no cardiovascular endpoint and no long-term safety data, and this board has a habit of treating pipeline numbers as settled.
One concrete data point for the thread. Say what you would expect to see if you were wrong, before you look. It is a small discipline and it changes what you notice.
Dr.PainCLE said:I would rather people stopped quoting the 24% as if it were a licensed outcome.
Adding the part of the answer the thread has not reached. Take it one variable at a time. Almost every unanswerable question in these threads is unanswerable because three things changed in the same fortnight, and no amount of subsequent argument can untangle them after the fact.
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Browse GL BiochemFollowing on from kim_atl_prep — and this may be the naive question:
What the phase 2 dropout pattern implies about how the phase 3 tolerability will read?
Reporting back.
Rereading it with the dropout table open changed my view. I still think it is the most interesting molecule in the pipeline; I no longer think the 24% is the number that will end up on a label.