julia.endo said:The useful move here is to separate what is established from what is widely repeated.
That holds where the measurement is reliable. Where it is noisy — and a lot of what gets tracked here is noisy — the same reasoning produces confident nonsense.
Ask again with the specifics and you will get a better answer than this one.
dan_philly said:The glucagon component looks paradoxical and is not.
Genuinely useful, thank you. I had the facts and not the framework.
julia.endo said:The useful move here is to separate what is established from what is widely repeated.
I read this differently. The confidence in this thread is running ahead of the evidence, and I would rather the uncertainty were stated than smoothed over because it is unsatisfying.
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Browse GL BiochemThe figures, for anyone assembling their own picture. The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the same conditions. Nobody wants that answer and it is still the answer.
Moderator note: leaving this open. It is being argued well and the disagreement is the useful part. Thread quality here is what the rules are for. Keep it up.