anders_CPH said:The GIP arm is doing real work rather than padding the label.
Agreed, with the usual condition: that holds for the average and this board is a collection of individuals. A population claim and a personal prediction are different things and get quoted interchangeably.
WendyG_ATL said:The glucagon component looks paradoxical and is not.
Thank you for spelling out the reasoning rather than just the conclusion.
anders_CPH said:The GIP arm is doing real work rather than padding the label.
I read this differently from anders_CPH, on substance rather than tone. The "tirzepatide is simply better" summary irritates me. It is better on mean weight loss, and the cardiovascular outcome evidence is far thinner than semaglutide's. If the reason for treating is cardiovascular risk rather than weight, the evidence base points the other way.
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