Clinical perspective, offered as context rather than as advice. The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either. Those three things can all be true at once, and most arguments here are two people holding different parts of that.
Correct me if the detail matters more than I have assumed.
TrialNerd_Beth said:The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either.
Same pattern here, and in the same order.
TrialNerd_Beth said:The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either.
Coming at TrialNerd_Beth’s question from a different direction. Start from the measurement rather than the conclusion. Almost every disagreement here turns out to be two people measuring different things and comparing the numbers anyway.
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View ResultsOne concrete data point for the thread. The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the same conditions. Nobody wants that answer and it is still the answer.
Happy to go further on any of that.
Following on from TrialNerd_Beth — and this may be the naive question:
How long did you give it before you decided it was working?