traveltech_sara said:SURMOUNT-1 landed around 20.9% mean weight loss at 15mg over 72 weeks, against roughly 15% for semaglutide 2.4mg in STEP 1.
This is exactly what I could not find anywhere else. I will report back once I have actually tried it.
Adding the clinical framing, because it changes how the question reads.
Month 8 update on sleep apnoea: down 20 lbs from my starting weight of 255 lbs. Here's what's changed beyond the scale:
- No longer pre-diabetic (A1C normalized)
- Off blood pressure medication
- Can tie my shoes without getting winded
- Sleep apnea resolved — returned my CPAP
- Confidence level: through the roof
This medication has genuinely given me my life back. I'm not exaggerating. 🙌
Dr.SleepRoch said:The GIP arm is doing real work rather than padding the label.
Sleep changes on sleep apnoea: anyone else sleeping differently? I've been sleeping worse since starting week 3.
My theory: the weight loss has improved my sleep apnea (confirmed by recent sleep study — AHI dropped from 28 to 4). Better oxygenation at night = better sleep quality = more energy during the day. It's a virtuous cycle.
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Browse GL BiochemOne concrete data point for the thread. Say what you would expect to see if you were wrong, before you look. It is a small discipline and it changes what you notice.
Moderator note: reminder that nothing in this thread is medical advice, and that clinical claims need a source. Thread quality here is what the rules are for. Keep it up.