Dr.GastroMayo said:It helps to say which part of this you are uncertain about.
Coming at Dr.GastroMayo’s question from a different direction. It is worth asking what the claim would look like if it were false. If nothing would look different, it is not a claim about the world and no amount of discussion will settle it.
One concrete data point for the thread. If you are going to change something, change one thing and give it long enough to express itself. Four weeks is the usual minimum for anything pharmacological on this board, and two weeks of data has told you almost nothing.
A narrower follow-up, since the general answer is now clear:
How would you tell the difference between that and the alternative explanation?
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Browse GL BiochemDanielChem_CHI said:If you are going to change something, change one thing and give it long enough to express itself.
This is where I part company with the consensus forming above. Pushing back on the anecdote-stacking. Twenty people reporting the same thing is twenty samples from the same self-selected pool, not twenty independent confirmations.
DanielChem_CHI said:If you are going to change something, change one thing and give it long enough to express itself.
That holds where the measurement is reliable. Where it is noisy — and a lot of what gets tracked here is noisy — the same reasoning produces confident nonsense.