mike_nyc said:Steady state is faster than people expect: half-life about five days, so you are at plateau in roughly three to four weeks rather than five.
This is where I part company with the consensus forming above. The "tirzepatide is simply better" summary irritates me. It is better on mean weight loss, and the cardiovascular outcome evidence is far thinner than semaglutide's. If the reason for treating is cardiovascular risk rather than weight, the evidence base points the other way.
One concrete data point for the thread. Worth stating the units and the reference range whenever you post a number here. A large fraction of the apparent disagreement in these threads is two people using different units and both being right.
BethLabQueen said:The "tirzepatide is simply better" summary irritates me.
Coming at BethLabQueen’s question from a different direction. It helps to say which part of this you are uncertain about. A precise question gets a precise answer; a general one gets everybody’s favourite anecdote.
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Browse GL BiochemOne thing that is still open after LipidDoc_ATL’s answer:
Whether anyone has held 10mg long term rather than climbing, and what happened over the following year?
OP back with an update, since a thread like this is useless without one.
Reporting back after another eight months at the same dose. Still losing slowly, no new side effects, and no reason I can find to climb further.