I split my weekly dose in half for six weeks to see whether it smoothed the first two days out, and the result was less impressive than I expected.
The question I want answered is what the pharmacokinetic argument against splitting a weekly dose actually is, since intuitively it should smooth the curve.
Numbers rather than impressions, if you have them.
steph_laguna said:I split my weekly dose in half for six weeks to see whether it smoothed the first two days out, and the result was less impressive than I expected.
Dose splitting update on split dosing: instead of 2.4mg once weekly, I've been doing 1.2mg twice weekly (Mon/Thu) with my doctor's approval. The appetite suppression is more consistent and side effects are noticeably milder.
Not medical advice, just sharing what's worked for me. Discuss with your provider before trying this.
Dr.MetabolicMD said:Dose splitting update on split dosing: instead of 2.4mg once weekly, I've been doing 1.2mg twice weekly (Mon/Thu) with my doctor's approval.
That is right for the common case. Whether it is right for the case being asked about depends on a detail that has not been given.
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Browse GL Biochemsteph_laguna said:I split my weekly dose in half for six weeks to see whether it smoothed the first two days out, and the result was less impressive than I expected.
Same experience, arrived at from the opposite direction.
Adding the clinical framing, because it changes how the question reads. It is worth asking what the claim would look like if it were false. If nothing would look different, it is not a claim about the world and no amount of discussion will settle it.